Ellen and Ronald Caplan Cancer Center

The mission of the Ellen and Ronald Caplan Cancer Center is to merge basic, translational and disease-relevant cancer research in a single scientific continuum with a focus on cancer prevention, diagnosis and therapy. The Ellen and Ronald Caplan Cancer Center has a history of significant advances in cancer genetics, cancer biology, tumor immunology, and virology, including the identification of genes associated with different tumor types, the development of monoclonal antibodies used to study pathways and proteins involved in tumor development, and contributions to improved cancer treatments and diagnostic tests.

The Ellen and Ronald Caplan Cancer Center is structured into three research programs. Taking an interdisciplinary approach to cancer research, our scientists are working to advance knowledge in the following areas:

1. The molecular pathways underlying some of the most prevalent and deadly types of cancer, to develop new targeted therapies and move forward in the direction of personalized cancer treatment
2. The crosstalk between tumor cells and the tumor microenvironment and how it orchestrates tumor progression and response to therapy
3. Cancer genomics and epigenetics
4. The mechanisms of therapy resistance and how they can be overcome
5. Tumor immunology and immunotherapy
6. Tumor cell metabolism and how it affects metastatic competence